Fibromyalgia & chronic fatigue syndrome
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Fibromyalgia, chronic fatigue, undiagnosed gastrointestinal problem
Taking anti-inflammatories
First, I find out what anti-inflammatory I can take at a high amount- alpha lipoic acid (200at start to 2400mg/day), turmeric w/a little black pepper, ginger, astaxanthin, boswellia, resveratrol, methylsulfonylmethane (MSM), bromelain, papain, nigella sativa, mangosteen, palmitoylethanolamide (PEA), cannabidiol (CBD) oil, Wobenzyme, Zyflamend, and Noni fruit. These can help with a lot of pain & inflammatory symptoms & make enduring a die-off response easier.
Alpha lipoic acid appears to be the strongest and fastest painkiller & anti-inflammatory against even migraines, nerve pain, & neuropathic pain and have no known significant side effects or drug interaction effects, and also appears to help control blood sugar, reverse heart disease, and cause significant weight loss at high doses- 500 mg when wake up, before each meal, and before bedtime (before nighttime munchies).
Heavy metal testing
I would get tested for heavy metals, including iron. Heavy metal poisoning & iron accumulation may all cause systemic problems including chronic fatigue and fibromyalgia. Lots of chelators that lower heavy metals are foods. One more symptom of iron overload is increased bacterial infections, which iron chelation may help along with prescription gallium. Iron levels may be safest for men when they are just above the borderline of too low.
Occipital nerve stimulation (ONS)
ONS may reduce pain intensity in six months by 44%.
Parasitic infection treatment
How to test/treat possible parasitic infection as cause- I try a combination antiparasitic for a week that has wormwood, black walnut, oregano oil, grapefruit seed extract, clove oil, raw garlic & onions, cayenne pepper, papaya (especially seeds), coconut oil, multistrain probiotics, cucumber seeds, ginger, turmeric w/a little black pepper, neem oil, diatomaceous earth, gentian root, blackberries, raw cabbage, aloe, pineapple, Berberine, uva ursi.
Prescription antiparasitics include i v e r m e c t i n & nitazoxanide.
Para-Shield, Paracomplete, & Doc Shillington’s blood detox are antiparasitic combinations.
https://draxe.com/parasite-cleanse-top-5-treatments-naturally-2/
https://blog.paleohacks.com/9-herbs-that-naturally-kill-parasites/
If no feeling of sickness (Herxheimer reaction from die off) after a week, then I save the rest & repeat in a year. If I have a die off reaction I continue taking for two weeks after the last symptoms.
Herpes treatment
In case of possible viruses in the herpes family like cytomegalovirus or Epstein-Barr which can cause systemic problems and can be underdiagnosed- I would take a 300-0500mg lysine capsule as frequently as comfortable for two days (and avoid eating nuts which have arginine) as well as at least 4000 IU of vitamin D3 & 500mg (lecithin) liposomal C both under tongue. The virus needs arginine but will use lysine if it’s in higher concentrations- and then die off.
Viral infections
In case of any other type of viral infection, I would take 5,000-10,000 units of vitamin D3 with a meal (fat soluble) daily for the rest of my life to get my levels at/higher than 70ng/ml, which appears to kill 90% of viral infections. I would also take liposomal vitamin C every two hours for two days, which appears to help kill almost all viruses and may be over 50X more effective than powdered vitamin C and seven times more effective than IV vitamin C. If no symptom relief after a couple days or if stools become loose then there may be no viral infection.
Lyme disease treatment
Taking whole leaf stevia, coconut oil (we make monolaurin from the lauric acid), samento & banderol and protease enzymes- serrapeptase, nattokinase, bromelain, grapefruit seed extract, papain, amylase, glucoamylase, N-acetyl L-cysteine, and boswelic acid that may help to kill lyme disease. If they are taken for a week and no die off reaction is observed, that may be enough. If there is one, they may continue to be taken for two weeks after the last die off reaction is observed.
Bacterial infections
I would then take antibacterials for a week (including avoiding iron which can increase bacterial infections) like multistrain probiotics, spirulina, liposomal vitamin C, vitamin D3, vitamin B3, gallium (by prescription), whole stevia leaf, coconut oil (lauric acid turns into monolaurin in body),
oregano oil, olive leaf, bee propolis, echinacea, elderberry, nigella sativa (black seed oil).
If I didn’t feel better after a week I would stop. If I did feel better I would keep taking it for another two weeks.
Fungal infections
I would then take antifungals for a week like vinegar (apple cider),
Candex (especially for stomach candida), liposomal vitamin C, oil of oregano, olive leaf extract, garlic, coconut oil (caprylic acid), colloidal silver, tea tree oil, undecylenic acid, neem oil, megafood high active enzymes, candizyme, alka-vita drops 20-40/day, boulardii, nystatin (prescription), cayenne, pau d’arco, ginger, tumeric w/a little black pepper, spirulina, and phellostatin. If I didn’t feel better after a week I would stop. If I did feel better I would keep taking it for another two weeks.
Autoimmune problems
Some autoimmune diseases like lupus can attack the organs and cause systemic problems & symptoms. I would avoid eating foods that can trigger inflammation like wheat, dairy, & sugar and nightshade plants that can trigger autoimmune reactions via their alkaloids like tomatoes & tomatillos, potatoes (sweet are ok), peppers (black is ok), eggplants, tobacco, okra, sorrel, paprika, gooseberries, pepino melons, ground cherries, and spices & “natural flavors” may contain nightshades. Blueberries, goji berries, and huckleberries may have similar alkaloids.
I would pressure cook all of my food to kill the lectins in so many plants that can increase symptoms in people with an autoimmune disorder.
I would take immune modulators for a week and see if symptoms got better (in order) like vitamin D3, royal jelly, low dose naltrexone, 1/8th ts baking soda 1-3x/day, spirulina (with a vegetable), probiotics, astragalus, ashwaganda, reishi, rehmannia, stephania, olive leaf, wormwood, and perhaps Indian sarsaparilla vine (hemidesmus).
If these all work I would continue taking them and consider asking my doctor to consider the antibiotic teicoplanin which kills the bacteria E. gallinarum that may be the cause of most autoimmune reactions when it escapes from the small intestine.
Magnesium
Having too little magnesium can cause or exacerbate a lot of fibromyalgia/chronic fatigue symptoms. Magnesium helps so many body systems like the heart & bones that taking extra magnesium may improve longevity. Some people take magnesium powder or pills, increasing the dosage until they get a little diarrhea. Then they cut back to half of that dosage for prevention, and they know how much more they can safely take if they have to treat active cramps/restless legs & migraines..
Magnesium malate & magnesium chloride may help fibromyalgia.
What else?
Elderberry & zinc, oregano oil, olive oil or leaf and a few other substances appear to have action against a lot of infectives.
Treatment combination for greatest potency.
I would combine all treatments at once because so many of the supplements/herbs treat multiple or all infections. This combined treatment is likely the key to killing off the infection completely.
Microcurrent
If I still felt bad I would buy a microcurrent device. The best setting may be 0.3hz and 0.5 mA or 500 microamps. This one is $49 and runs on a 9v battery or an AC adaptor.
InTENSity Micro Combo TENS & Microcurrent Combination Unit that requires batteries
Neo that also has TENS, inferential & muscle stimulation for $80 & a lithium rechargeable built in
This one is $89 and includes multiple pain relieving treatments but requires batteries
InTENSity Select Combo TENS, EMS, IF, & Microcurrent Unit + Free A/C Power Adapter Included
Wheat and dairy
Getting off of all wheat & dairy often clears up inflammation mediated symptoms, including serious chronic fatigue. Sometime IBS symptom resolve within a day.
Caused by an auto-immune reaction?
In one study on 15 people and another study on 29 people diagnosed with CFS the anti-arthritis drug rituximab, which destroys the immune system’s B cells, provided strong relief from CFS/ME in two thirds of patients. Because it takes months for the B cell level to fall, the drug starts working in four to six months and continues to work up to two years in one study.
The side effects of rituximab are increased viral infections, & possible cardiac arrest. It can cost over ten thousand dollars per treatment, and while it comes off patent this year, drug makers are using all kinds of tricks to prevent generics from reaching the shelves lately.
My take: the immunomodulators below are cheaper & have beneficial effects beyond their immunomodulating activity. If one can afford long term treatment on rituximab or if insurance companies start paying for it for CFS/ME, at least the increased viral infections may be countered by taking 5000 IU of vitamin D3 with a meal, and lipsomal C.
And know that since a drug that has a very specific immune effect- it treats diseases caused by too many B cells, overactive B cells, or dysfunctional B cells impaired- appears to successfully treat CFS/ME, it is just another disease caused by impaired B cell function, albeit one whose impairment hasn’t been explained yet. But the drug treatment, now in two separate studies, is direct evidence of a common & specific biological cause. Research will likely now focus on what B-cell impairment is causing CFS in two thirds of patients, should these results hold up in future studies.
B-Lymphocyte Depletion in Myalgic Encephalopathy/ Chronic Fatigue Syndrome. An Open-Label Phase II Study with Rituximab Maintenance Treatment
Øystein Fluge et al.
DOI: 10.1371/journal.pone.0129898
Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome: a preliminary case series
Øystein Fluge and Olav Mella
BMC Neurology 2009, 9:28 doi:10.1186/1471-2377-9-28
Immunomodulators
Here are some inexpensive immunomodulators without the immune lowering side effect of rituximab.
Immune modulators help regulate the immune system, lowering allergies & autoimmune diseases and increasing immune activity against infections & cancers.
Vitamin D3
Vitamin D3 deficiency has been sometimes diagnosed as fibromyalgia. Vitamin D3 is an immunomodulator that helps treat auto-immune and other diseases. 70-100 ng/ml is ideal if levels are tested. I take 5000 IU per day with a meal or vegetable oil (fat soluble) which has reduced my viral infections by 90%, & is supposed to reduce cancer by 70%, heart disease & death by 50%, diabetes by 70% and Alzheimers by over 90%.
Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis
Michael F Holick
Am J Clin Nutr March 2004 vol. 79 no. 3 362-371
Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study
John McBeth et al.
Ann Rheum Dis 2010;69:1448-1452 doi:10.1136/ard.2009.116053
A review of myofascial pain and fibromyalgia – factors that promote their persistence
Robert D Gerwin
Acupunct Med 2005;23:121-134 doi:10.1136/aim.23.3.121
Vitamin D deficiency in Fibromyalgia
Shaheen Ayuob Bhatty, Niaz Ahmed Shaikh, Muhammad Irfan, Syed Muhammad Kashif,
Aneel Sham Vaswani, Aneel Sumbhai, Gunpat
JPMA 60:949; 2010
Vitamin D levels in women with systemic lupus erythematosus and fibromyalgia.
A M Huisman, K P White, A Algra, M Harth, R Vieth, J W Jacobs, J W Bijlsma, and D A Bell
The Journal of Rheumatology vol. 28 no. 11 2535-2539
Myalgias or non-specific muscle pain in Arab or Indo-Pakistani patients may indicate vitamin D deficiency
Humeira Badsha, Mirna Daher, Kok Ooi Kong
Clinical Rheumatology
August 2009, Volume 28, Issue 8, pp 971-973
Di Rosa, M., Malaguarnera, M., Nicoletti, F. and Malaguarnera, L. (2011), Vitamin D3: a helpful immuno-modulator. Immunology, 134: 123–139. doi: 10.1111/j.1365-2567.2011.03482.x
Current Opinion in Pharmacology
Volume 10, Issue 4, August 2010, Pages 482–496
Cover image
Vitamin D: modulator of the immune system
Femke Baeke, Tatiana Takiishi, Hannelie Korf, Conny Gysemans, Chantal Mathieu
doi:10.1016/j.coph.2010.04.001
Journal of Neuroimmunology
Volume 194, Issues 1–2, February 2008, Pages 7–17
Vitamin D as an immune modulator in multiple sclerosis, a review
Joost Smolders, Jan Damoiseaux, Paul Menheere, Raymond Hupperts
doi:10.1016/j.jneuroim.2007.11.014
Nature Reviews Immunology 11, 584-596 (September 2011) | doi:10.1038/nri3045
Modulation of the immune system by UV radiation: more than just the effects of vitamin D?
Prue H. Hart, Shelley Gorman & John J. Finlay-Jones
Low dose naltrexone (LDN)
Naltrexone in large doses (50mg) is an opiate antagonist that is used to keep people addicted to opiates or alcohol from reusing. LDN is an immunomodulator that helps a number of auto-immune and other diseases like fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. It is available at compounded pharmacies by doctor’s prescription (see lowdosenaltrexone.org). LDN (3-12mg/night before sleep) significantly lessens pain in people with fibromyalgia/CFS.
Arthritis Rheum. 2013 Feb;65(2):529-38. doi: 10.1002/art.37734.
Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels.
Younger J1, Noor N, McCue R, Mackey S.
http://med.stanford.edu/snapl/research/ldn.html
http://updates.pain-topics.org/2013/12/more-evidence-that-naltrexone-aids.html
http://www.ldnresearchtrust.org/fibromyalgia
http://www.cortjohnson.org/treating-chronic-fatigue-syndrome-mecfs/drugs-for-chronic-fatigue-syndrome-mecfs-treatment/low-dose-naltrexone-ldn-fibromyalgia-chronic-fatigue-syndrom/
http://www.lowdosenaltrexone.org/index.htm#What_diseases_has_it_been_useful_for
Clin Rheumatol. 2014; 33(4): 451–459.
Published online 2014 Feb 15. doi: 10.1007/s10067-014-2517-2
PMCID: PMC3962576
The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain
Jarred Younger,corresponding author Luke Parkitny, and David McLain
The American Journal of Gastroenterology (2007) 102, 820–828; doi:10.1111/j.1572-0241.2007.01045.x
Low-Dose Naltrexone Therapy Improves Active Crohn’s Disease
Jill P Smith MD, Heather Stock MD, Sandra Bingaman RN, David Mauger PhD, Moshe Rogosnitzky and Ian S Zagon PhD
Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study
Jarred Younger PhD andSean Mackey MD, PhD
DOI: 10.1111/j.1526-4637.2009.00613.x
Volume 10, Issue 4, pages 663–672, May/June 2009
Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis†
Bruce A. C. Cree MD, PhD, MCR, Elena Kornyeyeva MD and Douglas S. Goodin MD
DOI: 10.1002/ana.22006
Annals of Neurology
Volume 68, Issue 2, pages 145–150, August 2010
Medical Hypotheses
Volume 64, Issue 4, 2005, Pages 721–724
Low dose naltrexone therapy in multiple sclerosis
Y.P. Agrawal
doi:10.1016/j.mehy.2004.09.024
Psychiatry Research
Volume 58, Issue 3, 16 October 1995, Pages 191–201
Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study
Manuel P. Bouvard, Marion Leboyer, Jean-Marie Launay, Christophe Recasens, Marie-Hélène Plumet, Delphine Waller-Perotte, François Tabuteau, Dominique Bondoux, Michel Dugas, Patrick Lensing, Jaak Panksepp
http://articles.mercola.com/sites/articles/archive/2011/09/19/one-of-the-rare-drugs-that-actually-helps-your-body-to-heal-itself.aspx
Royal Jelly
Royal jelly, a bee product, is an immune modulator.
Life Sciences
Volume 73, Issue 16, 5 September 2003, Pages 2029–2045
Major royal jelly protein 3 modulates immune responses in vitro and in vivo
Iwao Okamoto, , Yoshifumi Taniguchi, Toshio Kunikata, Keizo Kohno, Kanso Iwaki, Masao Ikeda, Masashi Kurimoto
doi:10.1016/S0024-3205(03)00562-9
International Immunopharmacology
Volume 7, Issue 9, September 2007, Pages 1211–1220
Fatty acids isolated from royal jelly modulate dendritic cell-mediated immune response in vitro
Dragana Vucevic, Eleni Melliou, Sasa Vasilijic, Sonja Gasic, Petar Ivanovski, Ioanna Chinou, Miodrag Colic
doi:10.1016/j.intimp.2007.05.005
Functional Properties of Honey, Propolis, and Royal Jelly
M. Viuda-Martos, Y. Ruiz-Navajas, J. Fernández-López andJ.A. Pérez-Álvarez
DOI: 10.1111/j.1750-3841.2008.00966.x
Journal of Food Science
Volume 73, Issue 9, pages R117–R124, November/December 2008
Comparative Immunology, Microbiology and Infectious Diseases
Volume 19, Issue 1, January 1996, Pages 31–38
A royal jelly as a new potential immunomodulator in rats and mice
Lidija Šver1, Nada Oršolić2, Zoran Tadić2, Bela Njari3, Ivica Valpotic, 1, Ivan Bašic2
doi:10.1016/0147-9571(95)00020-8
International Immunopharmacology
Volume 1, Issue 3, March 2001, Pages 521–532
Unraveling Mechanisms and Discovering Novel Roles for Complement
Suppression of allergic reactions by royal jelly in association with the restoration of macrophage function and the improvement of Th1/Th2 cell responses
Hideki Oka, Yutaka Emori, Naomi Kobayashi, Yoshiro Hayashi, Kikuo Nomoto
doi:10.1016/S1567-5769(00)00007-2
Stephania
Stephania may help against fibromyalgia.
Kang HS, Kim YH, Lee CS, et al. Anti-inflammatory effects of Stephania tetrandra S Moore on interleukin-6 production and experimental inflammatory disease models. Mediators Inflamm. 1996; 5(4:280–91.
Kwan CY, Achike FI. Tetrandrine and related bisbenzylisoquinoline alkaloids from medicinal herbs: cardiovascular effects and mechanisms of action. Acta Pharmacol Sin. 2002 Dec; 23(12):1057–68.
Sekiya N, Shimada Y, Niizawa A, et al. Suppressive effects of Stephania tetrandra on the neutrophil function in patients with rheumatoid arthritis. Phytotherapy Research. 2004; 18(3):247–9.
Caused by infection?
Many people with fibro or CFS/ME have chemical & biomarkers found in people who are fighting an infectious disease. In case it is a disease whose virus, bacteria, or fungi have not yet been found, 5000 IU of vitamin D3 (fat soluble) with a meal or veg oil has killed 90% of viral infections, 500 mg of liposomal vitamin C kills the rest, oregano oil & a multiple (ten different strains) probiotic (with a glass of water) as well as a bliss K-12 probiotic for the mouth (for strep throat) kills most strep throat & along with zinc & royal jelly helps kill bacterial infections, & the liposomal vitamin C kills at least fungal infections of the stomach.
See antiviral & antibacterial emails for details.
The herpes virus is the source of 8 different infections, from oral & genital herpes, to shingles & chicken pox, the Epstein-Barr virus, Cytomegalovirus, Roseolovirus, lymphotropic virus, Pityriasis Rosea, and Kaposi’s sarcoma.
The Epstein-Barr virus (EBV) can have symptoms like chronic fatigue syndrome symptoms:
Weariness, weakness and tiredness
Nasal congestion
Mild muscle aches
Sciatica
Neuritis
Disorders of the nerves
Insomnia
Nervousness
Anxiety
Irritability
http://hubpages.com/education/Lysine-for-Treating-Epstein-Barr-Virus-and-Chronic-Fatigue-Syndrome-Symptoms
http://www.sparkpeople.com/myspark/team_messageboard_thread.asp?board=5941x22376x60331482
http://www.healthy.net/Health/Article/Chronic_Fatigue_Syndrome/910
Source: Boundless. “Double-Stranded DNA Viruses: Herpesviruses.” Boundless Microbiology Boundless, 03 Jun. 2016. Retrieved 19 Jan. 2017 from https://www.boundless.com/microbiology/textbooks/boundless-microbiology-textbook/viruses-9/dna-viruses-in-eukaryotes-127/double-stranded-dna-viruses-herpesviruses-652-7104/
Lysine
The herpes virus needs arginine, an amino acid found in a lot of foods, to grow. The amino acid that kills the herpes virus is lysine, also found in a lot of foods. Killing the herpes virus appears to be a balance of lysine vs arginine intake. During an outbreak, avoiding foods with arginine should slow viral replication.
Foods that have more arginine than lysine:
nuts: peanuts, walnuts, hazelnuts, Brazil nuts, pecans, almonds may have the most arginine
seeds: sesame seeds, pumpkin seeds may have the most arginine
Grains: wheat, oats, rice may have the most arginine
fruits: grapes/raisons/wine/grape juice, blackberries, blueberries, tomatoes, grapefruit and oranges (including juice)
soy/tofu
Caffeine
Chocolate
Onions and garlic
During an outbreak, eating foods with lysine should help kill the herpes virus.
Foods that have more lysine than arginine:
Yogurt
Fish (not shellfish)
Meat including beef, lamb, chicken, turkey
Organic cheese and milk
stone fruit: (mango, apricots, cherries, avocados, papaya), apples, pears, figs and pineapples
http://www.livestrong.com/article/280245-shingles-and-lysinearginine-foods/
Alkalyzing the diet
Making the body more alkaline may help. Fruits (except citrus), vegetables, grains, beans (including tofu), lean poultry and fish can make the body more alkaline vs acid-producing foods like alcohol, coffee, refined sugars, citrus fruits, refined flour products, oils and fats.
http://www.healthy.net/Health/Article/Chronic_Fatigue_Syndrome/910/2
Lysine powder/capsules
Internal:
There is no larger or more concentrated source of lysine than lysine powder. Taking 1/4 ts or 500mg in a lysine capsule every three hours has killed my & people I know’s cold sores (HHV-1) in a day & people’s shingles (HHV-3) in a day that I know.
Topical:
Breaking open a capsule & mixing it just a little with the solvent DMSO, which also carries it very fast through the skin, killed my latest outbreak in a few hours.
Lysine safety
To treat EBV people have reportedly taken 1000mg of lysine three times a day for six months safely. Parkinson’s patients have taken over 4000mg per 100lbs body weight daily safely. Side effects of too much lysine can be diarrhea, nausea, and stomach pain. Lysine supplementation increases absorbtion & retention of calcium if taken together. People should see their doctor before taking lysine if they already have too much in their blood or urine from a special condition, or have kidney or liver impairment. For these people, treating lesions topically with the very small amount of lysine needed with the DMSO might be the safest treatment.
Lysine should not be taken with these drugs for safety reasons:
gentamicin (Garamycin);
tobramycin (Nebcin, TOBI);
amikacin (Amikin);
kanamycin (Kantrex);
netilmicin (Netromycin);
neomycin (Mycifradin, Neo-Fradin, Neo-Tab);
netilmicin (Netromycin);
streptomycin; or
tobramycin (Nebcin, Tobi).
http://hubpages.com/education/Lysine-for-Treating-Epstein-Barr-Virus-and-Chronic-Fatigue-Syndrome-Symptoms
https://www.drugs.com/npc/lysine.html
http://www.emedicinehealth.com/drug-lysine/page3_em.htm
Lysine. Review of Natural Products. Facts & Comparisons [database online]. St. Louis, MO: Wolters Kluwer Health Inc; February 2011.
So how many of these types herpes viruses does lysine work against?
Perhaps all of them. Lot’s of blogs & research studies show lysine’s efficacy against most of these herpes virus types. Taking up to 4g/day as Parkinsonian patients have done safely might kill an outbreak of any of the herpes viruses, if they are all as vulnerable as HH1, HH3, & HH4 have shown.
Lysine for chronic fatigue syndrome
As some of the side effects of EBV are similar to chronic fatigue syndrome, taking very inexpensive lysine capsules- as long as there are no of the above contraindications- may help if the source of the symptoms turns out to be EBV.
http://hubpages.com/education/Lysine-for-Treating-Epstein-Barr-Virus-and-Chronic-Fatigue-Syndrome-Symptoms
http://www.healthy.net/Health/Article/Chronic_Fatigue_Syndrome/910
http://www.vitality101.com/health-a-z/Infections-treating_hidden_viral_infections_cfs
https://www.victoriahealth.com/category/L-Lysine/302
Daily lysine supplementation? Avoid arginine?
Both lysine & arginine are needed for our immune system, recovering from injuries and reducing anxiety. If taking lysine & avoiding arginine works to immediately stop an occasional herpes outbreak, then people may be able to choose to avoid unnecessary lysine supplementation or arginine avoidance & create an imbalance of these two necessary amino acids.
For people who’s immunity is lower because of AIDS, other diseases, or medications, taking lysine prophylactically may prevent life threatening infection outbreaks & complications.
Singh BB, Udani J, Vinjamury SP, Der-Martirosian C, Gandhi S, Khorsan R, Nanjegowda D, Singh V. “Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes.” Altern Med Rev. 2005 Jun;10(2):123-7.
http://pharmascope.org/ijrps/downloads/Volume%202/Issue%204/25-121.pdf
Meenu Singh* , D. Muralidhara Rao , Shivansh Pande , Sowjanya Battu , Mahalakshmi. K , K. Rajeswar Dutt Medicinal Uses of L-Lysine: Past and Future Int. J. Res. Pharm. Sci., 2(4), 2011, 637-642
www.thepharmajournal.com/vol2Issue4/Issue_june_2013/2.1.pdf
Ms Radhika Devi M R, Prof. Dr. Yellina Haribabu, Mrs. Sheeja Velayudhankutty, Mrs. Sosamma Cicy Eapen, Ms Sujitha R Review on: Shingles, Its Complications &
Management THE PHARMA INNOVATION – JOURNAL Vol. 2 No. 4 2013
http://www.drwhitaker.com/treating-shingles-naturally/
http://www.wholehealthchicago.com/205/shingles/
http://healthwyze.org/index.php/component/content/article/370-how-to-eliminate-shingles-quickly-and-naturally-using-alternative-holistic-methods.html
http://pharmascope.org/ijrps/index.php/announce/download/209
http://www.webmd.com/vitamins-supplements/ingredientmono-237-lysine.aspx?activeingredientid=237&activeingredientname=lysine
Anti-inflammatories
Inflammation in the brain found by PET scans in one study are much higher in people with CFS/ME.
“The research team found increases in inflammatory markers in regions including the amygdala, thalamus and midbrain in CFS patients who had more severe cognitive troubles. They found more of these markers in thalamus and cingulate cortex in individuals who reported worse pain. And they found higher traces of inflammation in the hippocampus in patients with severe depression.
More than a decade ago, Watanabe’s group found tantalizing suggestions that certain neurotransmitters were not being synthesized as well in people with CFS. These patients also had lower levels of serotonin transporters in particular brain areas. Other research had found higher levels of inflammatory cell-signaling proteins called cytokines circulating in the blood. All of these results led Watanabe to look closer for inflammation.”
Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An 11C-(R)-PK11195 PET Study
Yasuhito Nakatomi et al.
J Nucl Med June 1, 2014 jnumed.113.131045
10.2967/jnumed.113.131045
Baffling Chronic Fatigue Syndrome Set for Diagnostic Overhaul
Researchers might soon redefine the mysterious condition, while the latest findings point to the role of brain inflammation
By Katherine Harmon Courage | May 16, 2014
http://www.scientificamerican.com/article/baffling-chronic-fatigue-syndrome-set-for-diagnostic-overhaul/
Alpha lipoic acid, tumeric with a little black pepper, ginger, resveratrol (Hu Zhang), astaxanthin, boswellia, bromelain (from pineapples), papain (from papaya)
Alpha lipoic acid, tumeric, ginger, resveratrol (Hu Zhang), astaxanthin, boswellia, bromelain (from pineapples), papain (from papaya) are all COX-2 inhibitors (just like aspirin & the other NSAIDS). They are major painkiller/anti-inflammatories as strong as aspirin but without its negative side effects of excessive bleeding & ulcers. Tumeric is a spice that’s in curry that works as well as aspirin but requires just a small amount (3/1000) of black pepper to increase its effectiveness by 200 times (increases curcumin in bloodstream). In a large number of people, turmeric raises their mood significantly. Ginger is a spice that not only is a major painkiller/anti-inflammatory, but it stops nausea as well as any prescription drug. Astaxanthin is an algae extract that is fat soluble that is not only a major painkiller/anti-inflammatory, but taken after ingestion it prevents the skin from burning in the sun starting at 10mg per day & prevents skin cancer, breast cancer, ulcers, cataracts, macular degeneration, skin wrinkling, & the dry chapped skin on the hands that I used to get every winter.
They should all be taken with a meal, and taken together they have helped people get off of opiates. They should get at the source of the inflammation & pain in people with fibromyalgia/CFS.
Food allergies/sensitivities
Fibromyalgia & CFS may be relieved to a degree by finding & ridding food allergies or sensitivities, including by foods that cause inflammation, as inflammation (including after exercise) is a hallmark of both diseases. Getting rid of all foods that have gluten is the first step, such as wheat, barley, & rye. Getting rid of gluten often treats irritable bowel syndrome. I got off of gluten because of a food sensitivity & from the first day my irritable bowel syndrome ended completely. Next is to get off of all dairy. People who get off of wheat & dairy often feel much better physically than ever before & lose up to thirty pounds.
Gluten is inflammatory. The types of wheat we used for millenia had up to 90% less gluten than our modern wheat, so wheat didn’t used to cause all the inflammatory problems it does now. Spelt is an older wheat with only a tenth as much gluten. When cooking with spelt it can’t be kneaded as much as the current high gluten wheat.
Pasteurized dairy products cause a lot of problems and digestive issues. Children who have an allergic reaction to dairy too often develop type one diabetes when the body mistakes insulin producing cells on the pancrease for the similar dairy molecules. Dairy also has growth hormone to exacerbate the essential problem with cow’s milk- it is very unlike human milk and is intended to grow an calf to 300 lbs.
Maca
Maca is a stimulating adaptogen that may help fibromyalgia or chronic fatigue, migraines, libido, & menopause.
http://www.healthysmoothiehq.com/what-is-maca-why-put-in-smoothie
http://www.onegreenplanet.org/vegan-health/why-you-should-replace-your-caffeine-fix-with-maca/
http://blog.familywize.org/2013/05/ditch-caffeine-habit-with-maca-root.html
http://www.collective-evolution.com/2014/01/06/this-superfood-could-replace-caffeine-viagra-meet-the-maca-root/
D-ribose
D-ribose is a sugar that may significantly reduce symptoms of CFS & fibromyalgia and also treats heart disease and congestive heart failure.
The Use of D-Ribose in Chronic Fatigue Syndrome and Fibromyalgia: A Pilot Study
Jacob E. Teitelbaum, Clarence Johnson, and John St. Cyr. The Journal of Alternative and Complementary Medicine. November 2006, 12(9): 857-862. doi:10.1089/acm.2006.12.857.
Adaptogens
Adaptogens are herbs that help give people energy if they are feeling tired or sick, but without the side effects of caffeine.
American ginseng root (Panax quinquefolius)
http://books.google.com/books?hl=en&lr=&id=7ipNZw0RBdgC&oi=fnd&pg=PP1&dq=eleuthero+stress&ots=FdswPjEzKE&sig=CogNSy8ENUJEuSSqDRfkYjRAXOo#v=onepage&q=eleuthero%20stress&f=false
http://www.sciencedirect.com/science/article/pii/S094471131100198X
http://www.tandfonline.com/doi/abs/10.1300/J044v06n02_11?journalCode=whsm20#.U8nC91HtnVM
http://www.sciencedirect.com/science/article/pii/S0378874107000086
Siberian ginseng root & leaf (eleuthero)
http://www.ingentaconnect.com/content/ben/ccp/2009/00000004/00000003/art00004
http://journals.lww.com/hnpjournal/Abstract/2008/07000/Deconstructing_an_Adaptogen__Eleutherococcus.8.aspx
http://richardallenmorris.com/how-to-reduce-stress-in-your-lifethe-secrets-of-adaptogens/
http://onlinelibrary.wiley.com/doi/10.1002/smi.914/abstract
Asian/Chinese/Korean ginseng (Panax)
http://www.paneuromix.com/koreaanse_ginseng_200_mg.html
http://www.researchgate.net/publication/224034499_Could_ginseng-based_medicines_be_better_than_nitrates_in_treating_ischemic_heart_disease_A_systematic_review_and_meta-analysis_of_randomized_controlled_trials?ev=prf_cit
http://www.update-software.com/BCP/WileyPDF/EN/CD007769.pdf
Rhodiola root also helps exercise, energy levels.
http://online.liebertpub.com/doi/abs/10.1089/acm.2007.7117
http://link.springer.com/article/10.1007/s11655-009-0177-x#page-1
http://europepmc.org/abstract/MED/21438645
http://www.sciencedirect.com/science/article/pii/S094471131000036X
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155223/
http://richardallenmorris.com/how-to-reduce-stress-in-your-lifethe-secrets-of-adaptogens/
Ashwaganda root also helps exercise, fatigue & low thyroid.
http://anabolicminds.com/forum/supplements/46804-ashwagandha-stress-reduction.html
http://www.chiro.org/nutrition/FULL/Stress_Hidden_Factor_For_Weight_Gain.shtml
http://www.ijrpbsonline.com/files/RS00020.pdf
http://www.chopra.com/files/docs/teacherdownloads/actpapers/Stress%20Fatigue%20Insomnia,%20Esta%20Venter.pdf
Schisandra seed & fruit also helps exercise, the liver, concentration, coordination, endurance according to Consumer Reports on Health. It can improve night vision by 90%.
http://www.ingentaconnect.com/content/ben/ccp/2009/00000004/00000003/art00004
http://onlinelibrary.wiley.com/doi/10.1002/ptr.2233/abstract
http://www.sciencedirect.com/science/article/pii/S0944711311001899
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155223/
Rhaponticum also helps exercise.
http://link.springer.com/article/10.1007/s11094-010-0387-8
http://books.google.com/books?hl=en&lr=&id=7ipNZw0RBdgC&oi=fnd&pg=PP1&dq=rhaponticum+stress&ots=FdswPjGwPK&sig=J6_mBxcncKvVuloGmJcihewVI-E#v=onepage&q=rhaponticum&f=false
http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYD200807017.htm
Jiaogulan
http://books.google.com/books?hl=en&lr=&id=7ipNZw0RBdgC&oi=fnd&pg=PP1&dq=jiaogulan+stress&ots=FdswPjGyQD&sig=ytooJj_00qOtEKxoilMjpALD2hU#v=onepage&q=jiaogulan&f=false
http://www.pharm.chula.ac.th/tjps/ContentVol36-sup/BP18.pdf
http://link.springer.com/article/10.1007/s11130-013-0399-0
Aralia mandchurica/elata spikenard root
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1264950
http://www.ijpc.ssjournals.com/index.php/journal/article/view/19
Holy Basil (Tulsi) helps anxiety, cholesterol, blood sugar, inflammatory, pain, radiation, cataracts.
http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summary_pr?p_JournalId=6&p_RefId=1118135&p_IsPs=N
http://nopr.niscair.res.in/handle/123456789/7955
Coenzyme Q/CoQ10
60-100mg of coenzyme Q10/CoQ10 helps people with congestive heart failure. Ubiquinol is the most effective form of CoQ10. It slows atherosclerosis, lowers inflammation, improves ischemia and reperfusion injury of coronary revascularisation, as well as exercise in people with CHF & hypertension.
In one study of 17 patients-
Heart function improved by 20%, and the mean CHF score increased significantly.
Left ventricular ejection fraction (a measure of the heart’s capacity to pump efficiently) improved nearly 35%.
Cardiac output improved by 15.7%.
Stroke volume index improved nearly 19%.
Systolic blood pressure decreased by 4.4%.
End-diastolic volume area decreased by 8.4%.
Mean exercise duration improved by 25.4%.
Cardiac workload improved by 14.3%.
http://www.lifeextensionvitamins.com/conhearfail.html#sthash.8rZHmyjr.dpuf
Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis1,2,3
A Domnica Fotino, Angela M Thompson-Paul, and Lydia A Bazzano
doi: 10.3945/â ajcn.112.040741
Am J Clin Nutr February 2013
Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia
Peter H. Langsjoen, MD, FACC, Alena M. Langsjoen, MS
The Asia Pacific Heart Journal
Volume 7, Issue 3, December 1998, Pages 160â 168
Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome
Adarsh Kumar, Harharpreet Kaur, Pushpa Devi, Varun Mohan
Pharmacology & Therapeutics
Volume 124, Issue 3, December 2009, Pages 259â 268
Journal of the International Society of Sports Nutrition
March 2008, 5:8,
Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals
Matthew Cooke, Mike Iosia, Thomas Buford, Brian Shelmadine, Geoffrey Hudson, Chad Kerksick, Christopher Rasmussen, Mike Greenwood, Brian Leutholtz, Darryn Willoughby, Richard Kreider
Coenzyme Q10 Supplementation and Heart Failure
Uma Singh , Sridevi Devaraj , Ishwarlal Jialal
Nutrition Reviews Volume 65, Issue 6 Pp. 286 – 293
DOI: http://dx.doi.org/10.1111/j.1753-4887.2007.tb00306.x 286-293
Molecular and Cellular Biochemistry
April 2003, Volume 246, Issue 1-2, pp 75-82
Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction
Ram B. Singh, Narankar Singh Neki, Kumar Kartikey, Daniel Pella, Adarsh Kumar, Mohammad Arif Niaz, Amar Singh Thakur
Role of Coenzyme Q10 in Chronic Heart Failure, Angina, and Hypertension
Dr. Mongthuong T. Tran Pharm.D.1, Dr. Tina M. Mitchell Pharm.D.2, Dr. Daniel T. Kennedy Pharm.D.3,* andDr. Joel T. Giles Pharm.D.4
DOI: 10.1592/phco.21.9.797.34564
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Volume 21, Issue 7, pages 797â 806, July 2001
The clinical investigator
August 1993, Volume 71, Issue 8 Supplement, pp S134-S136
Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study
Prof. C. Morisco, B. Trimarco, M. Condorelli
European Heart JournalVolume 27, Issue 22Pp. 2675 – 2681
Coenzyme Q10 and exercise training in chronic heart failure
Romualdo Belardinelli , Andi Muçaj , Francesca Lacalaprice , Maridia Solenghi , Giovanna Seddaiu , Federica Principi , Luca Tiano , Gian Paolo Littarru
DOI: http://dx.doi.org/10.1093/eurheartj/ehl158 2675-2681
Journal of Cardiovascular Nursing:
July 2002 – Volume 16 – Issue 4 – pp 9-20
Alternative Medicines for Cardiovascular Diseases
Coenzyme Q10 and Cardiovascular Disease: A Review
Sarter, Barbara PhD
L-carnitine
The amino acid L-carnitine ingestion (2g/day) appears to significantly improve symptoms in people with congestive heart failure, increasing exercise ability, and improving survival.
Beneficial effects of propionyl l-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction
Rajat Sethi , Ken S. Dhalla , Pallab K. Ganguly , Roberto Ferrari , Naranjan S. Dhalla
Cardiovascular Research Volume 42, Issue 3 Pp. 607 – 615
DOI: http://dx.doi.org/10.1016/S0008-6363(99)00089-9 607-615
The clinical and hemodynamic effects of propionyl-L-carnitine in the treatment of congestive heart failure
(PMID:1493661)
Pucciarelli G, Mastursi M, Latte S, Sacra C, Setaro A, Lizzadro A, Nolfe G
Servizio di Cardiologia, USL n. 42, Ospedale Elena D’Aosta, Napoli.
La Clinica Terapeutica [1992, 141(11):379-384]
Three-year survival of patients with heart failure caused by dilated cardiomyopathy and L-carnitine administration
Ioannis Rizos, MD
American Heart Journal
Volume 139, Issue 2, Supplement 2, February 2000, Pages s120â s123
Coronary Artery Disease:
February 2004 – Volume 15 – Issue 1 – pp 65-71
Improvement of cardiac function and β-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction
Sethi, Rajata; Wang, Xia; Ferrari, Robertob; Dhalla, Naranjan S.a
Controlled study on the therapeutic efficacy of propionyl-L-carnitine in patients with congestive heart failure.
Mancini M, Rengo F, Lingetti M, Sorrentino GP, Nolfe G
Università degli Studi di Napoli, II Facoltà di Medicina e Chirurgia, Italy.
Arzneimittel-Forschung [1992, 42(9):1101-1104]
Japanese Circulation Journal
Vol. 56 (1992-1993) No. 1 P 86-94
http://doi.org/10.1253/jcj.56.86
L-Carnitine Treatment for Congestive Heart Failure : Experimental and clinical study : CURRENT THERAPY OF INTRACTABLE HEART FAILURE
Akira Kobayashi, Yoshinori Masumura, Noboru Yamazaki
Evaluation of the therapeutic efficacy of L-carnitine in congestive heart failure.
Ghidini O, Azzurro M, Vita G, Sartori G
Reparto Medicina Interna, Ospedale Bussolengo, Verona, Italy.
International Journal of Clinical Pharmacology, Therapy, and Toxicology [1988, 26(4):217-220]
l-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure
Giorgio Vescovo, Barbara Ravara, Valerio Gobbo, Marco Sandri, Annalisa Angelini, Mila Della Barbera, Massimo Dona, Gianfranco Peluso, Menotti Calvani, Luigi Mosconi, Luciano Dalla Libera
American Journal of Physiology – Cell Physiology Published 1 September 2002 Vol. 283 no. 3, C802-C810 DOI: 10.1152/ajpcell.00046.2002
Hawthorn berry
900-1800 mg of hawthorn daily prevents & treats arrhythmia, congestive heart failure CHF, angina, arteriosclerosis, myocarditis, diarrhea, insomnia, plaque, clots, and kidney problems. Hawthorn increases exercise ability in people with CHF.
Efficacy of the Hawthorn (Crataegus) preparation LI 132 in 78 patients with chronic congestive heart failure defined as NYHA functional class II
U. Schmidt*, U. Kuhn, M. Ploch, W.-D. HübnerPhytomedicine
Volume 1, Issue 1, June 1994, Pages 17â 24
A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan ®) in the treatment of patients with congestive heart failure NYHA II
F.H. Degenringa, A. Sutera, M. Webera, R. Sallerb
Phytomedicine
Volume 10, Issue 5, 2003, Pages 363â 369
Hawthorn: pharmacology and therapeutic uses
JM Rigelsky and BV Sweet
American Journal of Health-System Pharmacy March 1, 2002 vol. 59 no. 5 417-422
Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials
Max H Pittler, MD, Katja Schmidt, MS, Edzard Ernst, MD, PhD
The American Journal of Medicine
Volume 114, Issue 8, 1 June 2003, Pages 665â 674
Hawthorn
Dr. Qi Chang PhD, Dr. Zhong Zuo PhD, Dr. Francisco Harrison MD, Dr. Moses Sing Sum Chow PharmD
DOI: 10.1177/00970002042006003
The Journal of Clinical Pharmacology
Volume 42, Issue 6, pages 605â 612, June 2002
Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure
Michael Tauchert, Prof Dr med
American Heart Journal
Volume 143, Issue 5, May 2002, Pages 910â 915
L-arginine
The amino acid L-arginine (nine grams per day) prolongs exercise duration and blood flow in people with congestive heart failure.
L-arginine supplementation prolongs exercise capacity in congestive heart failure.
(PMID:15226784)
Bednarz B, Jaxa-Chamiec T, Gebalska J, HerbaczyÅ ska-Cedro K, CeremuzyÅ ski L
Department of Cardiology, Postgranduate Medical School, Grochowski Hospital, Warsaw, Poland.
Kardiologia Polska [2004, 60(4):348-353]
Improvement of cardiac performance by intravenous infusion of l-arginine in patients with moderate congestive heart failure
Bella Koifman, MD; Yoram Wollman, PhD; Natalie Bogomolny, MD; Tamara Chernichowsky, MSc; Ariel Finkelstein, MD; Gary Peer, MD; Jack Scherez, BSc; Miriam Blum, MD; Shlomo Laniado, MD; Adrian Iaina, MD; Gad Keren, MD, FACC
J Am Coll Cardiol. 1995;26(5):1251-1256. doi:10.1016/0735-1097(95)00318-5
L-Arginine reduces heart rate and improves hemodynamics in severe congestive heart failure
Edimar Alcides Bocchi M.D.*, Alvaro Vilella De Moraes M.D., Antonio Esteves-Filho M.D., Fernando Bacal M.D., José Otavio Auler M.D., Maria José Carmona M.D., Giovanni Bellotti M.D. and Antonio Franchini Ramires M.D.
Clinical Cardiology
Volume 23, Issue 3, pages 205â 210, March 2000
DOI: 10.1002/clc.4960230314
Randomized, Double-Blind, Placebo-Controlled Study of Supplemental Oral l-Arginine in Patients With Heart Failure
Thomas S. Rector, PhD; Alan J. Bank, MD; Kathleen A. Mullen, RN; Linda K. Tschumperlin, RN; Ronald Sih, MD; Kamalesh Pillai, MD; Spencer H. Kubo, MD
Circulation 1996; 93: 2135-2141
doi: 10.1161/01.CIR.93.12.2135
Correction of endothelial dysfunction in chronic heart failure: additional effects of exercise training and oral L-arginine supplementation
Rainer Hambrecht, MDa; Lutz Hilbrich, MDa; Sandra Erbs, BSca; Stephan Gielen, MDa; Eduard Fiehn, MDa; Nina Schoene, MDa; Gerhard Schuler, MDa
J Am Coll Cardiol. 2000;35(3):706-713. doi:10.1016/S0735-1097(99)00602-6
Hawthorn, coenzyme Q (ubiquinol), carnitine, and arginine appear in multiple studies to help congestive heart failure.
Herbs and Dietary Supplements in the Prevention and Treatment of Cardiovascular Disease
Adriane Fugh-Berman MD
DOI: 10.1111/j.1520-037X.2000.80355.x
Issue Preventive Cardiology
Preventive Cardiology
Volume 3, Issue 1, pages 24â 32, Winter 2000
Taurine
The amino acid taurine (2g 2x/day) helps slow the progression of congestive heart failure and improve survival.
Therapy of congestive heart failure with orally administered taurine.
Azuma J, Hasegawa H, Sawamura A, Awata N, Ogura K, Harada H, Yamamura Y, Kishimoto S
Clinical Therapeutics [1983, 5(4):398-408] (PMID:6871923)
The potential health benefits of taurine in cardiovascular disease
Yan-Jun Xu, MD PhD, Amarjit S Arneja, MD, Paramjit S Tappia, PhD, and Naranjan S Dhalla, PhD MD (Hon) DSc (Hon)
Exp Clin Cardiol. 2008 Summer; 13(2): 57â 65.
PMCID: PMC2586397
Therapeutic effect of taurine in congestive heart failure: A double-blind crossover trialâ
J. Azuma M.D.*, A. Sawamura M.D., N. Awata M.D., H. Ohta M.D., T. Hamaouchi M.D., H. Harada M.D., K. Takihara M.D., H. Hasegawa M.D., T. Yamagami M.D., T. Ishiyama M.D., H. Iwata M.D. andS. Kishimoto M.D.
Clinical Cardiology
Volume 8, Issue 5, pages 276â 282, May 1985
DOI: 10.1002/clc.4960080507
Taurine: An overview of its role in preventive medicine
Barry S. Kendler, Ph.D.
Preventive Medicine
Volume 18, Issue 1, January 1989, Pages 79â 100
doi:10.1016/0091-7435(89)90056-X
American Heart Journal
Volume 112, Issue 6, December 1986, Pages 1278â 1284
Beneficial effect of taurine in rabbits with chronic congestive heart failure â
Keiko Takihara, M.D., Junichi Azuma, M.D., Nobuhisa Awata, M.D., Hideyuki Ohta, M.D., Tomoyuki Hamaguchi, M.D., Akihiko Sawamura, M.D., Yuya Tanaka, M.D., Susumu Kishimoto, M.D., Nick Sperelakis, Ph.D.
European Journal of Pharmacology
Volume 180, Issue 1, 3 May 1990, Pages 119â 127
The effects of taurine on atherosclerosis development in cholesterol-fed rabbits
Margaret A. Petty, Jacqueline Kintz, Giuseppe F. DiFrancesco
Journal of Cardiology
Volume 57, Issue 3, May 2011, Pages 333â 337
Effect of taurine supplementation on exercise capacity of patients with heart failure
Mohamad Reza Beyranvand, MD, Mahshid Kadkhodai Khalafi, MS, Valiollah Dabidi Roshan, PhD, Sirrus Choobineh, PhD, Saeid Alipour Parsa, MD, Mohammad Asadpour Piranfar, MD, PhD
Cordyceps mushroom
Treatment of arrhythmias with cordyceps has a an 82% success rate on average, including a majority of people with superventricular arrhymia, ventricular arrhythmia or complete blockage of the right branch ECG recovery, tachyarrhythmia & brachyarrhythmia, including premature beats. Cordyceps lowers total cholesterol, triglycerides, & beta lipoprotein (low density cholesterol).
In people with heart failure, cordyceps increases cardiac stroke volume and cardiac index, general physical & emotional well being and quality of life & reduces heart rate, shortness of breath, & fatigue.
The Scientific Rediscovery of a Precious Ancient Chinese Herbal Regimen: Cordyceps sinensis Part II
Jia-Shi Zhu, Georges M. Halpern, Kenneth Jones
The Journal of Alternative and Complementary Medicine. Winter 1998, 4(4): 429-457.
doi:10.1089/acm.1998.4.429.
Saunas
Sauna usage improves ventricular arrhythmias in people with chronic heart failure.
Effects of Repeated Sauna Treatment on Ventricular
Arrhythmias in Patients With Chronic Heart Failure
Takashi Kihara, MD; Sadatoshi Biro, MD; Yoshiyuki Ikeda, MD; Tsuyoshi Fukudome, MD;
Takuro Shinsato, MD; Akinori Masuda, MD; Masaaki Miyata, MD; Shuichi Hamasaki, MD;
Yutaka Otsuji, MD; Shinichi Minagoe, MD; Suminori Akiba, MD*; Chuwa Tei, MD
Circ J 2004; 68: 1146 â 1151
Endothilial cell function is essential to the health of the arteries & heart, especially in people with heart disease. Sauna usage improves endothilial, heart, & exercise functioning.
Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure.
Kihara T1, Biro S, Imamura M, Yoshifuku S, Takasaki K, Ikeda Y, Otuji Y, Minagoe S, Toyama Y, Tei C.
J Am Coll Cardiol. 2002 Mar 6;39(5):754-9.
Repeated sauna therapy increases arterial endothelial nitric oxide synthase expression and nitric oxide production in cardiomyopathic hamsters.
Ikeda Y1, Biro S, Kamogawa Y, Yoshifuku S, Eto H, Orihara K, Yu B, Kihara T, Miyata M, Hamasaki S, Otsuji Y, Minagoe S, Tei C.
Circ J. 2005 Jun;69(6):722-9.
Am J Cardiol. 2012 Jan 1;109(1):100-4. doi: 10.1016/j.amjcard.2011.08.014. Epub 2011 Sep 23.
Effect of repeated sauna treatment on exercise tolerance and endothelial function in patients with chronic heart failure.
Ohori T1, Nozawa T, Ihori H, Shida T, Sobajima M, Matsuki A, Yasumura S, Inoue H.
Sauna usage helps the functioning of people with heart failure.
Exp Clin Cardiol. 2007 Spring; 12(1): 29â 32.
PMCID: PMC2359619
Clinical Cardiology: Review
Beneficial effects of sauna bathing for heart failure patients
Nava Blum, PhD1 and Arnon Blum, MD2
Using a sauna just twice weekly can increases endurance by 30%.
J Sci Med Sport. 2007 Aug;10(4):259-62. Epub 2006 Jul 31.
Effect of post-exercise sauna bathing on the endurance performance of competitive male runners.
Scoon GS1, Hopkins WG, Mayhew S, Cotter JD.
Using a sauna increases muscle growth & stops soreness.
Intermittent hyperthermia enhances skeletal muscle regrowth and attenuates oxidative damage following reloading.
Selsby JT1, Rother S, Tsuda S, Pracash O, Quindry J, Dodd SL.
J Appl Physiol (1985). 2007 Apr;102(4):1702-7. Epub 2006 Nov 16.
Using a sauna can significantly increase insulin sensitivity & lower blood sugar levels.
Int J Hyperthermia. 2007 May;23(3):259-65.
Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice.
Kokura S1, Adachi S, Manabe E, Mizushima K, Hattori T, Okuda T, Nakabe N, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T.
Human growth hormone HGH prevents muscle loss & atrophy, as does testosterone. Levels of HGH drop off dramatically after the age of thirty, and testosterone drops significantly as well. Supplementing them artificially can increase cancer & have other serious physical & behavioral side effects. Sauna usage naturally raises HGH & testosterone levels.
Eur J Appl Physiol Occup Physiol. 1989;58(5):543-50.
Haemodynamic and hormonal responses to heat exposure in a Finnish sauna bath.
Kukkonen-Harjula K1, Oja P, Laustiola K, Vuori I, Jolkkonen J, Siitonen S, Vapaatalo H.
NSAID usage
NSAIDs usage may lead to congestive heart failure at greater rates than even gastrointestinal issues.
Consumption of NSAIDs and the Development of Congestive Heart Failure in Elderly PatientsAn Underrecognized Public Health Problem FREE
John Page, MBBS(Hons); David Henry, MBChB
Arch Intern Med. 2000;160(6):777-784. doi:10.1001/archinte.160.6.777
What may increase metabolism
Malic magnesium has been reported to increase energy. Magnesium is an essential supplement that helps leg cramps, migraines, constipation, bone building and helps treat a myriad of other health problems. I take up to 2000 mg of magnesium daily.
Onions, mustard, & all peppers all increase metabolism & energy more than any other foods in one British study. I’ve tested this when at the ballpark & its cold eating onion relish with mustard DID keep me significantly warmer.
Coconut & MCT oil has medium chain triglycerides that increase energy unlike every other type of fat- weightlifters & runners take two tablespoons before working out.
Green tea has EGCG which increases metabolism.
Being in the cold or drinking cold water increases metabolism.
Right after eating immediately engaging in walking or light to moderate exercise boosts metabolism.
The Wim Hof method- no longer feel cold/hot/stress/autoimmune overreaction
Wim Hof is a Dutch man who learned to become immune to cold, heat, & control his immune response to a strong degree. He has been in ice up to the neck in a tub for almost 2 hours. He has ran a marathon in a desert at 104 degrees with no water or food, and one above the Arctic circle barefoot. He has killed an injected bacteria that should have made him very sick in a medical experiment. Now he is teaching others how to do it, and it only takes one minute a day & people get big benefits after just the first time.
In this link is an explanation of how to do this his way, which includes meditation, a breathing method, and cold exposure:
http://highexistence.com/the-wim-hof-method-revealed-how-to-consciously-control-your-immune-system/
Here is the simplified one minute a day version-
If you have a heart or lung condition ask your doctor if fast breathing & holding your (non) breath is ok for you. If you are sick you can wait until healthy before starting. Wim Hof wisely recommends only doing this from a secure sitting position for safety.
What I found important is heavy breathing for oxygenation for 30 breaths/30-60 seconds, then breathing out completely & holding the nonbreath (empty lungs) until my body makes me take a breath (15-30 seconds). It’s ok if the first time is only 15 seconds, our ability gets a little better every time.
Wim Hof recommends exercising during the breath holding like pushups or some other exercise on the ground to avoid falling. I do it after eating my rice (carbs) so I have the energy for the exercise, but if people would rather just hold the breath it appears to work nearly as well. The carbs also give me the energy for the heavy breathing so I have the energy to do it twice a day after eating carbs rather than just once.
After I did this once for one minute I was able to be comfortable in my apartment at three degrees colder than ever before for a full day (57 degrees). Every time I do this I am able to experience greater & greater amounts of cold. Wif Hof recommends testing ourselves with cold showers or ice buckets, but I have seen all the benefits without.
I have tested myself by being very comfortable after one week in my apartment in the low 50s for hours. Most people don’t like the cold and the knowledge they don’t have to do the cold challenge but will still lose their sensitivity to cold makes it more likely they will do the exercise. We know its working when we walk outside in the cold & it doesn’t bother us anymore & we don’t feel like turning on our car to warm it up anymore.
One funny thing about the ability to endure cold- my knees still don’t like long exposure to cold temperatures even if the rest of my body has no problem:-)
Conscious control of cold & heat
Wim Hof suggests paying attention to how the body feels & consciously giving energy to different parts, especially if they are cold. This is supposed to give conscious control of our body temperature. I did this in a sauna when too hot to stay in & thought about being cool inside & I was soon comfortable enough to stay another 40 minutes. Meditating seems to improve the conscious control of body temperature. I’ve also done this when out in the cold & it works just as well.
Control of stress
I didn’t read that the breathing technique also helps the stress response, but I have found that if I feel stress I can lower it consciously in a way different than just meditation. It feels like a conscious control of my cortisol levels (the stress hormone).
Autoimmune responses
He & the people he trains have been able to kill bacterial infections that should have made them very sick in an experiment after just 90 repetitions. That’s three months when doing it once a day. It appears that their bodies are shutting down the overactive immune response to the bacterial infection. Other people have noted their autoimmune disorders (like rheumatoid arthritis) being helped greatly by the breathing method.
http://www.paddisonprogram.com/wim-hof-reversing-autoimmune-diseases/
http://www.medicaldaily.com/natural-inflammation-treatment-breathing-exercises-and-ice-baths-may-quell-immune-337890
https://www.newscientist.com/article/dn26102-three-ways-the-iceman-controls-his-immune-system/
http://www.livingflow.net/influence-immune-system-at-will/
http://www.livingflow.net/wim-hof-method-autoimmune-disease-rheumatoid-arthritis/
Cold exposure?
So I suspect that we get the benefits even if we don’t do the extreme cold exposure and that holding our nonbreath/empty lungs is the key. Doing this once a day is easily possible (I do it after eating so I have the energy) and results start immediately. This is a funny kind of body hack that changes more than any other I’ve ever learned to help us be comfortable and stress and autoimmune problems free.
Conscious control over internal temperature
What the extreme cold exposure coupled with meditating on being warm appears to do is give conscious control over body temperature, especially with practice. We can all use this when we are in a situation we feel cold in despite the Wim Hof method’s help.
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SAMe!
vitD3
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warm pool exercise
red rice yeast may cause
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milnacipran(Savella) more norep than serato
triptyline (Elavil)
cyclobenzaprine(Flexaril)
pregabalin (Lyrica)
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hormone check
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Xyrem(sodium oxybate)
gabapentin (Neurontin)
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theanine
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chromium
vinegar
cordyceps
cantaloupe
kelp noodles
pickles
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sourkraut.
raw grapefruit causes fat 2 B burned
mineral salt
green leafys
oat straw extract
vitB100s
D-ribose
alpha lipoic acid
Karin Berndl and art director Nici Hofer Vinegar Socks
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