To Jesus:

 

 

Saving this to a “Health” email folder may make access easier.

You can use this as an aide to your own research and share with your doctor as appropriate.

You can use drugs.com or other trusted health websites to look up the latest information on
prescription drugs, herbs, foods or other treatments possible side & interaction effects.

 

 

Schizophrenia

 

 

Causes

 

Influenza & schizophrenia

 

It is suspected that children develop the vulnerability to schizophrenia that may manifest later in
life from the pregnant mother’s exposure to the flu. A child is seven times more likely to develop
schizophrenia later in life if she comes down with the flu in the first trimester.
The safest preventative with the best outcomes is for the expectant mother to take 4000 IU of
vitamin D3 with a meal or vegetable oil (fat soluble) daily to reduce her chances of getting a viral
infection by 90%, and which will also reduce the chances of hospitalization of the infant after
childbirth by 80%, and for the mother preeclampsia by 80%, Caesarean section by 75%,
gestational diabetes by 67%, and bacterial vaginitis by 50% compared to ones with low levels.
Low vitamin D3 levels after the children are born make them at least 400% more likely to get a
lower respiratory infection.

www.vitaminDcouncil.org

http://www.thetp.org/article/view/462/532

http://www.vitamindcouncil.org/newsletter/newsletter-pregnancy-and-gestational-vitamin-d-defici
ency/#

 

The other explored causes are prenatal rubella, toxoplasma gondii (T-gondii) exposure usually
by handling/being in the room with cat feces or unwashed produce/uncooked meat, herpes,
Lyme disease, polio, chlamydia, measles.

 

 

T-gondii

T-gondii makes men more suspicious and can trigger paranoid schizophrenia as well as ADHD symptoms in men & women if they are genetically vulnerable. Even men without the genetic vulnerability
to schizophrenia can develop an aversion to cats (of whom half carry T-gondii) from increasing
paranoia & ADHD symptoms. T-gondii makes women more empathetic towards cats (the main
carriers) and triggers schizophrenia as well. It is the science behind the (amusing but often
true) stereotypes of “cat hating boyfriends” & “crazy cat ladies” where men sometimes refuse to
live with cats without knowing why, and women sometimes come to hoard too many cats than
they can take care of.

Toxoplasma gondii levels are three times higher on average with people with schizophrenia.
Washing all vegetables, fully cooking all meat, & avoiding being in the room or in a house with
unventilated cat feces should help lower the amount of T-gondii levels in the body and the
attendant schizophrenic symptoms.

 

Seroreactive marker for inflammatory bowel disease and associations with antibodies to dietary
proteins in bipolar disorder Emily G. Severance et al.
Bipolar Disord. 2014 May; 16(3): 230–240. doi: 10.1111/bdi.12159
en.wikipedia.org/wiki/Toxoplasmosis#.22Crazy_cat_lady_syndrome.22

 

 

Cytomegalovirus

Cytomegalovirus levels are four times higher in people with schizophrenia.

 

 

Taking 2g of elderberry every 8 hours with 50mg zinc daily may end symptoms within a day.

 

Taking 4000IU of
vitamin D3 with a meal or vegetable oil (fat soluble) prevents 90% of viral infections.

Neriman, A., Hakan, Y. & Ozge, U. The psychotropic effect of vitamin D supplementation on schizophrenia symptoms. BMC Psychiatry 21, 309 (2021). https://doi.org/10.1186/s12888-021-03308-w

G. Fond et al. Hypovitaminosis D is associated with depression and anxiety in schizophrenia: results from the national FACE-SZ cohort Psychiatry Res.(2018)

 

 

The amino acid lysine fools the cold sore family of viruses (cytomegalovirus, shingles/chicken pox, Epstein-Barr) into thinking it is arginine so lysine supplementation appears to prevent/treat cytomegalovirus infections & may lower schizophrenia episodes.

 

Taking 500mg-1g of lecithin liposomal vitamin C daily should help as a strong antivirus.

 

 

Hallucinogens (legal & otherwise)

 

 

Along with T-gondi, other triggers have been shown to be associated with schizophrenic
symptoms. Taking ANY drug with a side or main effect of hallucinations can trigger
schizophrenic episodes in people with the genetic vulnerability to schizophrenia- including
marijuana, LSD, peyote, PCP, the prescription antianxiety drug hydroxyzine (Vistaril), the sleep

supplement valerian, many of the Parkinson’s drugs etc.

 

Prescription drugs’ side effect lists
need to be scrutinized with care for people not only with schizophrenia to avoid, but people with
a genetic vulnerability/family history of schizophrenia to sidestep. It is very possible with the treatments listed below for people with a genetic susceptibility for schizophrenia to avoid ever having a first psychotic break if the triggers like hallucinogens are avoided in the first place, as well as to prevent subsequent schizophrenic episodes in people with already active schizophrenia.

 

 

Tobacco usage

People with schizophrenia are three times more likely to smoke tobacco.
http://apt.rcpsych.org/content/6/5/327.full

It’s possible that smoking is a way to have nicotine make up for the lower levels of gamma-aminobutyric acid in the brains of people with schizophrenia.

Theanine, an amino acid which increases gamma-aminobutyric acid to help anxiety during the
day/sleep at night & improves memory & learning, may help to stop the need for nicotine to fill
the gap.

ncbi.nlm.nih.gov/pubmed/17182482
news.sciencemag.org/2008/10/why-schizophrenics-smoke
ncbi.nlm.nih.gov/pubmed/17182482
suite.io/laura-owens/w40266
overcomingyouranxiety.net/naturalanxietyremedies/theanine-for-anxiety/
hoffmancenter.com/page.cfm/417

The earlier the treatment comes after symptoms start to show, the better the function in the
present & future.

ncbi.nlm.nih.gov/pubmed/23109356
europepmc.org/abstract/MED/9847047
psycnet.apa.org/psycinfo/1998-04528-013
psycontent.com/content/b48674u77783jg80/
ncbi.nlm.nih.gov/pmc/articles/PMC1118427/

 

Wheat & dairy

Going wheat (and all gluten) and milk free often lowers or halts schizophrenic episodes,
especially over long periods. Corn & soy, chocolate & eggs can be tested as well. It appears to work faster for people newer to diagnosis. People with schizophrenia may have antibodies to gliadin like with celiac disease, but with a different immune response, possibly IgG.

 

This therapeutic effect is not unique to schizophrenia. Hundreds of books & tens of thousands
of parents & doctors have documented that going milk/dairy & wheat free increases social understanding & reduces sensory processing disorder for many people who are autistic- autism.com.
psychologytoday.com/blog/evolutionary-psychiatry/201103/wheat-and-schizophrenia
bjp.rcpsych.org/content/115/522/595.short
orthomolecular.org/library/jom/1980/pdf/1980-v09n04-p284.pdf
psycnet.apa.org/journals/szb/14/4/489/
sciencemag.org/content/191/4225/401.short
ajp.psychiatryonline.org/article.aspx?articleID=153205
orthomolecular.org/library/jom/1990/pdf/1990-v05n04-p223.pdf
sciencedirect.com/science/article/pii/0006322394001764
ncbi.nlm.nih.gov/pmc/articles/PMC1604665/pdf/brmedj00126-0055a.pdf
aut.sagepub.com/content/3/1/85.short
sciencedirect.com/science/article/pii/030698779190215K

 

 

 

 

Age of the father

In a couple where the man is over 40 the child has a 2% chance of schizophrenia, six times
greater chance of autism, nine times after 50yrs old.

mothers35plus.co.uk/older-fathers.htm

standard.co.uk/news/article-23365716-details/Older+dads+six+times+more+likely+to
+have+autistic+children/article.do

 

 

Health and schizophrenia

There’s some evidence that people with schizophrenia are three times more likely to die of heart
disease than average & 1.5X more likely to die of cancer, even though they may be half as likely
to get cancer.
Atypical antipsychotics, schizophrenia, and cardiovascular risk: What family physicians need to
know
BCMJ, Vol. 50, No. 8, October 2008, page(s) 444-450
Nupura Krishnadev et al.
bcmj.org/article/atypical-antipsychotics-schizophrenia-and-cardiovascular-risk-what-family-physicians-need-know
ncbi.nlm.nih.gov/pmc/articles/PMC1277021/

 

 

People with schizophrenia also have three times the hypothyroidism, eight times the hepatitis C
infections, two times the asthma & diabetes.
Better education about physical symptoms leads to better medical compliance.

 

 

Wheat gluten and schizophrenia

The gluten in wheat and other grains may trigger or increase the frequency of schizophrenic
episodes.
Schizophr Res. 2010 May;118(1-3):248-55. doi: 10.1016/j.schres.2009.08.009. Epub 2009 Sep
11.

Novel immune response to gluten in individuals with schizophrenia.
Samaroo D, Dickerson F, Kasarda DD, Green PH, Briani C, Yolken RH, Alaedini A.

 

 

 

Ketogenic diet

 

A ketogenic diet appears to significantly reduce schizophrenic symptoms, likely by avoiding the legumes (beans, lentils, peanuts) & grains than if not organic are heavy with glyphosate/ROundup.

 

 

 

Eye Movement Desensitization and Reprocessing (EMDR)

 

EMDR may help some of the symptoms of schizophrenia.

 

theepochtimes.com/health/schizophrenia-symptoms-causes-treatments-and-natural-approaches-5660614?src_src=Bright&src_cmp=bright-2024-06-25&est=AAAAAAAAAAAAAAAAbOAichQfyNXo%2FKEBqmpXBrVzxw0NKCTCYUwurypk8oz0wXydwpyA

 

 

Self awareness

For people with schizophrenia who don’t believe they need medications/natural supplements to
help their symptoms, videotaping schizophrenic episodes for playback (for their eyes only)
increases medication taking significantly. Prescribing supplements & medications that don’t
have life shortening side effects like diabetes & obesity & life altering ones like tardive
dyskenisia also help compliance significantly.

 

Prescription antipsychotics

The majority of antipsychotics cause weight gain & diabetes which may lead to increased
chances of dying from both cancer or heart disease. Quetiapine (Seroquel) also causes the
heart to sometimes skip a beat which made it the sixth most deadly drug in 2009 behind
oxycodone. It probably would have been number one if the diabetes it causes were factored in.

haydeninstitute.com/additional-resources/additional-resources-medication-and-side-effects
/astrazeneca-suppressed-information-about-seroquel-link-to-diabetes-told-sales-reps-to-lie
journals.lww.com/jonmd/Abstract/2004/01000/Serious_Cardiovascular_Events_and_Mortality_Among.4.aspx
sciencedirect.com/science/article/pii/S0163834309001418

corporatecrime.wordpress.com/2009/12/03/astrazeneca-tales-of-a-deadly-drug-pusher/

 

Few if any of the prescription antipsychotics help overall physical & mental health.

consumerhealthchoices.org/wp-content/uploads/2012/08/BBD-Antipsychotics-Full.pdf

 

 

Alternative therapies

 

InterVoiceonline.org is a website that helps people understand, come to terms with, & even
explore hearing voices for its own value & not always as a negative experience.
Continuous assertive community treatment, family treatment or individual & group treatment,
social skills training all help. Learning medical managment, coping with symptoms, and
decreasing stress are essential.

 

 

Spirulina- more than 2x as effective as prescription antipsychotics

 

Spirulina is an algae that fish eat that gives them their EPA & DHA omega 3 fatty acids so prized
in fish oil. In the December 2009 issue of the Harvard Mental Health Letter, after a review of
many years of research Harvard psychiatrists concluded that fish oil was at least twice as
effective as any prescription antipsychotic in preventing and treating schizophrenic episodes.
The reason Harvard psychiatrists came to this conclusion is because the omega3 fatty acids in
fish oil, EPA & DHA, have shown repeatedly in the last 50 years to prevent & stop emerging
schizophrenia far better than the newer or older antipsychotics and without their often extreme
side effects. The main other effect of EPA & DHA fatty acids is an increase in mood and ability
to concentrate, which improves the quality of life of the people taking it far beyond just the
prevention of schizophrenic episodes.
Some researchers have found low EPA/DHA in autopsies of people with schizophrenia.
Perhaps it is an inability to retain enough EPA & DHA for many people genetically predisposed
to schizophrenia that contributes to the disease itself. People who enter studies & start taking
EPA & DHA usually continue taking it after the study is done.

Spirulina, like the fish oil it is always in, needs to be taken with a vegetable for the enzymes to help break it down & for it to be fully effective.

sciencedirect.com/science/article/pii/S0920996400000839
link.springer.com/article/10.1007/BF02637070
onlinelibrary.wiley.com/doi/10.1002/%28SICI%291099-1077%28199601%2911:1%3C39::
AID-HUP742%3E3.0.CO;2-%23/abstract
journals.psychiatryonline.org/article.aspx?articleid=175765
raysahelian.com/schizophrenia.html
sciencedirect.com/science/article/pii/S0920996400000839
J Clin Med. 2016 Aug; 5(8): 67.
Published online 2016 Jul 27. doi: 10.3390/jcm5080067

Supplementation with Omega-3 Fatty Acids in Psychiatric Disorders: A Review of Literature
Data
Paola Bozzatello, Elena Brignolo, Elisa De Grandi, and Silvio Bellino

 

Hsu M.-C., Huang Y.-S., Ouyang W.-C. Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: Possible mechanisms. Lipids Health Dis. 2020;19:159. doi: 10.1186/s12944-020-01337-0. – DOI – PMC – PubMed

 

Spirulina- more than 4x as effective as placebo

At seven year followup to earlier research comparing EPA & DHA fatty acids to placebo found
that those who had briefly taken EPA & DHA fatty acids seven years ago when they were
experiencing early symptoms of schizophrenia had progressed to schizophrenia at 300% lower rate of those who had gotten a placebo. The EPA & DHA fatty acids were more than 400%
better at preventing emerging schizophrenia, even after taking them for only a brief duration.
Nature Communications, DOI:10.1038/ncomms8934

 

 

If you want to get the EPA & DHA omega3 fatty acids that are great for the brain that are in
some kinds of fish oil without the off taste or worry about pesticides, mercury or radiation (in the
Pacific), you can get EPA & DHA from where fish get them- from taking the algae called
spirulina. At ovega.com is a good explanation of how EPA & DHA omega 3 fatty acids in fish
come from eating the algae spirulina. Ovega.com is the company inspected by the FDA that
supplies 99% of the baby formulas with EPA & DHA for supplementation. I use and trust NOW
Foods and Source Naturals. For spirulina Ovega.com is also reputable and they grow it in
stainless steel vats for purity.

 

 

Spirulina and vegetables

 

When I took spirulina I only got the full concentration & mood boosting effects when I ate it with
a meal with a vegetable (of any color). I got no benefit from eating it with a legume & grain. It
might have something to do with the enzymes needed to break it down. Only 1/4 teaspoon two
to three times a day with a meal with a vegetable is needed to significantly improve mood and
concentration, but as people with schizophrenia may need more and as there are little or no
negative side effects people can experiment on their own.

 

Here’s a great study showing EPA & DHA omega3 fatty acids improves mood:
lef.org/magazine/mag2007/oct2007_report_depression_01.htm
nutraingredients-usa.com/Research/EPA-stands-alone-as-a-depression-fighter
improves concentration & reduces ADHD:
ncbi.nlm.nih.gov/pmc/articles/PMC1971271/
articles.mercola.com/sites/articles/archive/2013/08/19/omega-3-fat-dha.aspx

 

 

lowered violence in prisoners:
psychologytoday.com/blog/evolutionary-psychiatry/201105/diet-and-violence

reduced bipolar symptoms of depression and mania and increased mood:
psycheducation.org/depression/meds/Omega-3.htm
mclean.harvard.edu/pdf/news/mitn/satevnpost.stoll0605.pdf
ncbi.nlm.nih.gov/pubmed/18072818

 

 

Flaxseed oil as a spirulina substitute

For people who can’t take spirulina, flaxseed oil has the most ALA, the third omega3 fatty acid.
Because of the sensitivity of the polyunsaturated fats it needs to be uncooked, expeller pressed,
unrefined and organic may be best. The body can make some DHA & EPA from ALA,
especially if vitamin B100s, zinc, magnesium, and vitamin C are taken as well. Spirulina worked
for me, & when I discovered my food sensititivities I started taking ALA & vitB100s, zinc, magnesium & natural or lecithin liposomal vitamin C together.
whfoods.com/genpage.php?tname=george&dbid=76
tackleacne.com/omega-3-fatty-acids.html

 

 

Cannabidiol (CBD)

Perhaps the most surprizing treatment of schizophrenic hallucinations is cannabidiol (CBD),
which comes from hemp (marijuana with no/trace THC). The marijuana plant evolved to cause
hallucinations so animals would eat it & distribute its seeds far & wide. The compound, THC,
that it evolved to cause hallucinations is often not pleasant by itself, as people who take marinol
(synthesized THC) by prescription often report. So the marijuana plant evolved another
cannabanoid, cannabidiol, to take the edge off the hallucinations. Turns out, when people take
cannabidiol by itself, it is a powerful anti-hallucinogen.

 

Marijuana can have low CBD because THC competes with it for the plant’s resources, and
people who smoke marijuana often want higher THC than the CBD. Hemp has the most CBD
as it doesn’t have to compete with THC. Hemp oil with CBD is completely legal to buy &
possess in all of the USA, because if its negligible THC content. People often get confused
between the legality in buying hemp products and the illegality of buying marijuana.

 

The other benefits of cannabidiol are:

Antiepileptic/anticonvulsant-it can work in people unresponsive to other drugs for uncontrolled
seizures
Low dose it’s alerting & high dose it’s sleep increasing
Anti-inflammatory
Anxiolytic (antianxiety)
Anti-emetic (antinausea)

Analgesic
Anticancer
Immunomodulator-improves immune action against threats & reduces auto-immune disorders
Helps against IBD and Crohn’s Disease
Neuroprotectant
Antioxidant

It may help Alzheimer’s, Parkinsons, cerebral ischemia, brain and nerve damage from strokes.
unitedpatientsgroup.com/blog/2013/01/06/cannabidiol-facts/
examine.com/supplements/Hemp+Protein/
scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400001&lng=en&nrm=iso&tlng=en
en.wikipedia.org/wiki/Cannabidiol#cite_note-Leweke_2012-13
nature.com/tp/journal/v2/n3/full/tp201215a.html
greenbridgemed.com/2013/03/08/cannabidiol-and-schizophrenia/
europeanneuropsychopharmacology.com/article/S0924-977X%2813%2900332-5/ab
stract

 

 

Lithium (schizoaffective)

For people who have schizoaffective disorder (both schizophrenia and depression or bipolar
illness) lithium reduces suicides & self harm better than all anticonvulsants in people with
schizoaffective disorder who also have mania.

psycnet.apa.org/psycinfo/1982-04097-001

onlinelibrary.wiley.com/doi/10.1111/j.1600-0447.1984.tb01202.x/abstract?deniedAccessCustomisedMessage=&userIsAuthenticated=false
link.springer.com/article/10.1007/BF02916252

 

 

L-theanine

L-theanine has been tested to help anxiety during the day and sleep at night as well as the
“positive” symptoms of schizophrenia with no negative side effects.

med.nyu.edu/content?ChunkIID=653856

researchgate.net/publication/49731066_L-theanine_relieves_positive_activation_and_anxiety_symptoms_in_patients_with_schizophrenia_and_schizoaffective_disorder_an_8-week_randomized_double-blind_placebo-controlled_2-center_study

aminoacidinformation.com/theanine-helps-treat-anxiety-in-schizophrenia/
psychweekly.com/aspx/article/articledetail.aspx?articleid=1248
wellnessresources.com/studies/l-theanine_bdnf_cortisol_and_schizophrenia/
ncbi.nlm.nih.gov/pubmed/21208586
journals.lww.com/clinicalneuropharm/Abstract/2011/07000/Serum_Levels_of_Brain_Derived_Neurotrophic_Factor.6.aspx

 

 

Magnesium glycinate at night

 

 

L-glycine appears to help anxiety during the day & sleep at night as well as helping the “negative” symptoms of schizophrenia.
schizophrenia.com/glycinetreat.htm
livestrong.com/article/489535-niacin-glycine-for-schizophrenia/
webmd.com/vitamins-supplements/ingredientmono-1072-GLYCINE.aspx?activeIngredientId=1072&activeIngredientName=GLYCINE
med.nyu.edu/content?ChunkIID=21751
ncbi.nlm.nih.gov/pmc/articles/PMC1760744/
ebmh.bmj.com/content/8/3/82.full

 

 

 

 

L-GABA

While there is little research on the amino acid L-GABA for schizophrenia, it also relieves
anxiety during the day and helps sleep at night.
webmd.com/vitamins-supplements/ingredientmono-464-GABA%20%28GAMMA-AMI
NOBUTYRIC%20ACID%29.aspx?activeIngredientId=464&activeIngredientName=GABA%20%28GAMMA-AMINOBUTYRIC%20ACID%29
livestrong.com/article/337555-do-gaba-supplements-improve-sleep-panic-anxiety/Vitamins C, Bs, & zinc

 

 

 

Vitamins C & B3

 

Some people’s symptoms respond strongly to taking high doses of vitamin C and vitamin B3. Liposomal vitamin C is between 5-10 times more effective than powdered vitamin C.

 

Lecithin liposomal vitamin C appears effective against candida infection, which may be a trigger for schizophrenia.

 

doctoryourself.com
orthomolecular.org/library/jom/2008/pdf/2008-v23n04-p191.pdf
link.springer.com/article/10.2165/00003495-198530010-00006#page-1

 

`

 

 

People with paranoid schizophrenia may respond well to folate (vitB9) supplementation, zinc
plasma testing & supplementation (as needed) as well as eating a diet low in copper, and by
avoiding SAM-e, SSRIs and methionine.

 

 

People with schizophrenia may respond to methylcobalamin, vitamin B12.

 

People with schizophrenia may respond well to high dose vitamin B6 supplementation (both PH
& PLP together) if levels are low to bring them up to normal, as well as vitamin B3 (niacin or
niacinamide) and lecithin liposomal vitamin C.

William J. Walsh, Nutrient Power, 2012
Taking a daily dose of 100mg of all the B vitamins (sold as vitamin B100s) can increase
concentration, especially as we get older.

psychsocgerontology.oxfordjournals.org/content/56/6/P327.short
ajcn.nutrition.org/content/82/3/627.short

 

 

Vitamin B9 (folate)

High homocysteine levels (perhaps above 8 μmol/L) appear to increase schizophrenia. Many
people (60% of the population, and 90% of people with depression) can’t use regular folate well
which may contribute to high homocysteine levels. Taking methylfolate (methyl version of
vitamin B9) may increase folate blood levels 700% higher than synthetic folate and may reduce
homocysteine levels much lower. Lowering homocysteine may also reduce depression,
dementia, bipolar disorder, anxiety, cardiovascular disease, congestive heart failure, stroke,
migraines, age-related macular degeneration, and hearing loss.

 

 

 

Sustained releave vitamin B complex

 

Since people with schizophrenia can respond effectively to vitamin B3, B6, B9 & B12, taking a sustained release B complex after breakfast may help symptoms.

 

 

What else lowers homocysteine-
vitamin B6, vitamin B12 (methylcobalamin may be best), betaine (TMG), vitamin B2, and

magnesium
n-acetyl L-cysteine (NAC)
S-adenosylmethionine (SAMe)
taurine
green vegetables, especially dark green leafy vegetables
oranges
beans
exercise

 

 

What to avoid
the prescription drugs cholestyramine, colestipol, fenofibrate, levodopa, metformin,
methotrexate, niacin, nitrous oxide, pemetrexed, phenytoin, sulfasalazine
red meat and dairy products
smoking
coffee
alcohol consumption
advancing age
obesity

Reduced B Vitamin Therapy in MTHFR C677T/A1298C Patients with Major Depressive Disorder
– Clinical Response Correlates with Homocysteine Reduction: A Double-Blind,
Placebo-Controlled Study Arnie Mech and Andrew Farah

enlyterx.com/wp-content/uploads/2015/11/EnLyte-Clinical-Study-Reprint.pdf
globenewswire.com/news-release/2015/07/29/756168/10143796/en/Breakthrough-Depression-Study-Shows-42-Remission-Rate-With-EnLyte.html
drweil.com/health-wellness/body-mind-spirit/heart/elevated-homocysteine/

 

 

Cognitive remeditation therapy CRT

CRT helps people with schizophrenia, & in one study physically changed brain activity in people
with schizophrenia.

bjp.rcpsych.org/content/181/2/144.short
journals.psychiatryonline.org/article.aspx?articleid=106958
psychiatrictimes.com/schizophrenia/cognitive-rehabilitation-schizophrenia
schizophreniabulletin.oxfordjournals.org/content/37/suppl_2/S80.full
bjp.rcpsych.org/content/190/5/421.long
journals.psychiatryonline.org/article.aspx?articleid=99253

 

 

D-serine

D-serine is an amino acid which is often at low levels in people with schizophrenia & may help lower symptoms significantly when supplemented. As amino acids are found in our foods & usually have little or no negative side effects.

 

ncbi.nlm.nih.gov/pubmed/9836012
archpsyc.jamanetwork.com/article.aspx?articleid=207549
ncbi.nlm.nih.gov/pubmed/22853788
plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062438
ncbi.nlm.nih.gov/pmc/articles/PMC3111070/
raysahelian.com/schizophrenia.html
ebmh.bmj.com/content/8/3/82.full
news-medical.net/news/20121018/Plasma-D-serine-levels-reduced-in-schizophrenia.aspx
researchgate.net/publication/230594420_D-serine_and_schizophrenia_an_update

 

Huperzine

Huperzine is an herb that increases concentration by increasing choline in the brain and calming
overactive glutamate activity in the brain. Huperzine helps most people’s concentration but
especially people with autism, ADHD, Alzheimers, and/or schizophrenia, as they also have
overactive glutamate. 200mg every four hours was what I eventually built up to that worked well. Note that if you take huperzine it is good to take supplemental choline or get it in foods it is
common in, like cauliflower. You can look up what foods have the most choline. I used source
naturals brand but always recommend buying in bulk (often powder) once you know it works for
you if powder form is available.

webmd.com/vitamins-supplements/ingredientmono-764-HUPERZINE%20A.aspx?activeIngredientId=764&activeIngredientName=HUPERZINE%20A
webmd.com/vitamins-supplements/ingredientmono-764-HUPERZINE%20A.aspx?activeIngredientId=764&activeIngredientName=HUPERZINE%20A
forum.bodybuilding.com/showthread.php?t=6779761
synmr.com/index.php?ac=article&at=read&did=156

 

 

Indian snakeroot (Rauwolfia)

 

Indian snakeroot is the source of reserpine, the first medication used for high blood pressure.  It alse appears to help schizophrenia symptoms. Reserpine as Respen-A has been used to help people with autism for decades.

 

 

homoeopathicjournal.com/articles/1099/8-1-69-153.pdf

sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/rauvolfia-serpentina

 

 

Ashwaganda

 

Ashwaganda, also possibly in a mix with other adaptogens, may lower stress enough to reduce schizophrenic symptoms significantly.

psychiatrist.com/jcp/withania-somnifera-extract-for-schizophrenia-symptoms/

 

Gingko

 

Gingko is traditionally used to prevent dementia, but also appears to significantly reduce symptoms of schizophrenia.

 

 

 

Yokukansan

 

Yokukansan is a mix of Angelica, Atractylodes, Bupleurum, Poria, Glycyrrhiza, Cnidium, and Uncaria that appears to reduce schizophrenia symptoms greatly.

 

 

Sarcosine

 

Sarcosine is in a lot of foods and in concentrated for it helps reduce schizophrenic symptoms,
especially depression.
archpsyc.jamanetwork.com/article.aspx?articleid=209027
ncbi.nlm.nih.gov/pubmed/23562005
ncbi.nlm.nih.gov/pubmed/16275807
schizophreniaoptions.com/sarcosine/
ncbi.nlm.nih.gov/pubmed/17659263
europepmc.org/abstract/MED/19562643

 

 

N-acetylcysteine NAC

 

NAC appears to help reduce the symptoms of schizophrenia better than many other interventions.

ncbi.nlm.nih.gov/pmc/articles/PMC3044191/
ncbi.nlm.nih.gov/pmc/articles/PMC3036554/
nature.com/npp/journal/v33/n9/abs/1301624a.html
sciencedirect.com/science/article/pii/S0006322308002709
sciencedirect.com/science/article/pii/S0959438809000440

 

D-Alanine

D-Alanine also shows promise in relieving the negative and positive symptoms of schizophrenia.
sciencedirect.com/science/article/pii/S0006322305008462

 

 

Transcranial Magnetic Stimulation TMS

TMS may help reduce schizophrenic symptoms.

europepmc.org/abstract/MED/17388712
tmsct.com/uploads/documents/TMS_Meta_Analysis.pdf
sciencedirect.com/science/article/pii/S1935861X08000375
sciencedirect.com/science/article/pii/S0304394004014600
brainstimjrnl.com/article/S1935-861X%2811%2900129-X/abstract
sciencedirect.com/science/article/pii/S0920996403003475

ncbi.nlm.nih.gov/pmc/articles/PMC4558786/

 

 

Cognitive Enhancement Therapy (CET) can help people with schizophrenia or autism with
cognitive ability & social skills.
cognitiveenhancementtherapy.com/
cetcleveland.org/

 

BP 157

 

BP 157 appears to reduce the symptoms of schizophrenia & depression

 

Sikiric, P., et al. (2013). Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. Journal of Physiology and Pharmacology, 64(1), 123-134.

Torkildsen, O., et al. (2008). The cuprizone model for demyelination. Acta Neurologica Scandinavica, 118(3), 141-148.

Herring, N. R., & Konradi, C. (2011). Myelin, copper, and the cuprizone model of schizophrenia. Frontiers in Bioscience, 16, 1231-1243.

Vukojevic, J., et al. (2022). Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats. Neural Regeneration Research, 17(3), 482-487.

Klicek, R., et al. (2013). Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. Journal of Physiology and Pharmacology, 64(1), 123-134.

 

 

 

 

 

Zonisamide

Zonisamide is a seizure reducing medication that also appears to help Parkinson’s & Lewy Body
disease symptoms as well as tardive dyskinesia & migraines & may help schizophrenia.

 

 

Prodromal-attention probs, soc withd, phys clumsiness

 

Biomarkers for schizophrenia

In this cohort, 22 proteins predicted subsequent schizophrenia with sensitivity of 89% and
specificity of 66%. Adding positive-symptom subscores from CARMMS yielded 89% sensitivity
and increased specificity to 79%, far better values than achieved with CARMMS scores alone.
Chan MK et al. Development of a blood-based molecular biomarker test for identification of
schizophrenia before disease onset. Transl Psychiatry 2015 Jul 14; 5:e601.
(http://dx.doi.org/10.1038/tp.2015.91)

 

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