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Niacinamide (nicotinamide)
Niacinamide is a no hot flush version of vitamin B3, and a penny per day. It has a mild bitter taste that can be mediated by stevia if taken under the tongue for faster, stronger & longer effect.
Niacinamide appears to turn on mitochondria to increase mental & physical energy & stop cancer, reduce viral infection symptoms including reducing progression to AIDS from HIV infection over seven years in one study & covid symptoms (including kidney injury) in other studies. It appears to reduce liver fat (in a mouse study), triglycerides & vLDL, & increase the good cholesterol HDL that helps to clean out arteries. Taken under the tongue, orally or topically it may build keratin & help acne, rosacea & sunburn, and topically wrinkles & most skin disorders. Niacinamide may reduce schizophrenia symptoms by over 50% & may significantly reduce anxiety & depression from alcohol cessation, fat accumulation, arthritis & reduce neurodegenerative disease symptoms like with dementia & Parkinson’s.
mwhp.com/niacin-the-powerhouse-vitamin-you-are-not-hearing-about/
curology.com/blog/niacinamides-powerful-benefits-for-your-skin/
Sahin, K., Kucuk, O., Orhan, C. et al. Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis. Sci Rep 11, 14724 (2021). https://doi.org/10.1038/s41598-021-94142-3
Dosage
Studies have found the full benefits at 1mg/lb of weight, like 50mg 3x a day if 150lbs. Because 1/4th of a teaspoon can be 500mg, the effective dosage may be 1/32 ts 3x a day for people around 175lbs.
People may be taking enough & getting a fully effective dosage when they feel a large increase in mental & physical energy- mitochondria are fully turned on.
The easiest way most people I know dose is to buy a set of measuring spoons- tad 1/4 ts, dash 1/8 ts, pinch 1/16 ts, smidge 1/32 ts, drop 1/64 ts & start with a drop 1/64 ts three times a day under the tongue. If they don’t feel the full energy effect the next day they increase to the next highest dose until feeling a large boost in mental & physical energy, which means it is fully working. When bought in bulk these daily doses can be less than a penny, which makes niacinamide the cheapest highly effective treatment for cancer, ADHD, diabetes, heart disease, depression etc. existing.
ncbi.nlm.nih.gov/pmc/articles/PMC2921576/
healthline.com/nutrition/niacinamide
oh17.com/2022/07/08/low-dose-niacinamide-has-striking-antiobesity-effects-dr-mercola/
Chen A.C., Martin A.J., Choy B., Fernández-Peñas P., Dalziell R.A., McKenzie C.A., Scolyer R.A., Dhillon H.M., Vardy J.L., Kricker A., et al. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. N. Engl. J. Med. 2015;373:1618–1626. doi: 10.1056/NEJMoa1506197. nejm.org/doi/full/10.1056/NEJMoa1506197
Ilias P. Nikas, Stavroula A. Paschou, Han Suk Ryu. (2020) The Role of Nicotinamide in Cancer Chemoprevention and Therapy. Biomolecules 10:3, 477. ncbi.nlm.nih.gov/pmc/articles/PMC7175378/
Eija Pirinen, Mari Auranen, Nahid A. Khan, Virginia Brilhante, Niina Urho, Alberto Pessia, Antti Hakkarainen, Juho Kuula, Ulla Heinonen, Mark S. Schmidt, Kimmo Haimilahti, Päivi Piirilä, Nina Lundbom, Marja-Riitta Taskinen, Charles Brenner, Vidya Velagapudi, Kirsi H. Pietiläinen, Anu Suomalainen, Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy, Cell Metabolism, Volume 31, Issue 6, 2020, Pages 1078-1090.e5, ISSN 1550-4131, doi.org/10.1016/j.cmet.2020.04.008. sciencedirect.com/science/article/pii/S155041312030190X)
nature.com/articles/d42473-022-00002-7.pdf
bengreenfieldlife.com/transcripts/transcript-new-anti-aging-supplement/
