Guanfacine

 

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Guanfacine (Tenex)

 

Guanfacine is a drug that lowers blood pressure.  It also appears effective for many for ADHD, Tourette’s syndrome, autism & for aggression.  People usually start on the lowest dosage (1mg extended release once a day) & increase once a week to the most effective dosage for that person (4mg extended release is usually the maximum).  It appears to be most effective in children up to 12 years old. It is often given in the evening as it may increase sedation/sleepiness/fatigue at first.

 

medicalnewstoday.com/articles/325695

drugs.com/comments/guanfacine

 

Rating of the Effectiveness of 26 Psychiatric and Seizure Medications for Autism Spectrum Disorder: Results of a National Survey. Coleman DM, Adams JB, Anderson AL, Frye RE. J Child Adolesc Psychopharmacol. 2019 Mar;29(2):107-123. doi: 10.1089/cap.2018.0121. Epub 2019 Feb 6. PMID: 30724573; PMCID: PMC6442266.

fulltext as link on ASU website- autism.asu.edu/about

liebertpub.com/doi/full/10.1089/cap.2018.0121?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

 

DeFilippis M, Wagner KD. Treatment of Autism Spectrum Disorder in Children and Adolescents. Psychopharmacol Bull. 2016 Aug 15;46(2):18-41. PMID: 27738378; PMCID: PMC5044466.

ncbi.nlm.nih.gov/pmc/articles/PMC5044466/

 

About the author

MD has worked through severe lifelong developmental disabilities (and a brain injury) with much more success than the medical press suggests is possible. He is motivated to share his research and personal experiences with everyone who wants it, and doesn't solicit payment.