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Low dose naltrexone (LDN)
LDN low dose naltrexone 3-5g at bedtime helps:
Chronic pain
Opiate addiction
Cancer
Autism
Aggression
Alzheimers
Hepatitis C
Parkinson’s
Diabetic neuropathies
Dermatomyositis (an inflammatory muscle disease)
Autoimmune disorders-
Chronic fatigue/fibromyalgia
Celiac
Colitis
Crohns
IBS
Lupus
MS
Rheumatic
Psoriasis
ALS
Ulcerative colitis
Multiple sclerosis
HIV/AIDS
Hasimoto’s thyroiditis
Irritable bowel syndrome (IBS)
Lowdosenaltrexone.org
“The latest research in Experimental Biology and Medicine just confirmed that LDN does in fact target the opioid growth factor (OGF)/opioid growth factor receptor (OGFr) pathway to inhibit cell proliferation. Previous research by professor Ian S. Zagon of The Pennsylvania State University, who also conducted the Experimental Biology and Medicine study, found that OGF regulates the growth of cancer cells, and all cancer cells use the OGF-OGFr pathway in growth regulation.”
“Typically, LDN is taken at bedtime, which blocks your opioid receptors, as well as the reception of endorphins, for a few hours in the middle of the night. This is believed to up-regulate vital elements of your immune system by increasing your body’s production of metenkephalin and endorphins (your natural opioids), hence improving your immune function.”
Best results cancers of the bladder, breast, liver, lung, lymph nodes, pancreas, colon, and rectum.
LDN combined with a chemotherapy drug, cisplatin, alleviated the toxicity associated with cisplatin.
Exp Biol Med (Maywood). 2011 Sep;236(9):1036-50. doi: 10.1258/ebm.2011.011121. Epub 2011 Aug 1.
Low-dose naltrexone targets the opioid growth factor-opioid growth factor receptor pathway to inhibit cell proliferation: mechanistic evidence from a tissue culture model.
Donahue RN, McLaughlin PJ, Zagon IS.
PUBLIC RELEASE: 2-SEP-2011
Low-dose naltrexone (LDN): Tricking the body to heal itself
SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE
http://www.eurekalert.org/pub_releases/2011-09/sfeb-ldn090211.php
articles.mercola.com/sites/articles/archive/2011/09/19/one-of-the-rare-drugs-that-actually-helps-your-body-to-heal-itself.aspx
Opiate addiction & LDN
LDN appears to reduce pain & cravings for opiates in people who are addicted.
Autism & LDN
“75% parents of autistic children surveyed reported that LDN delivered overall beneficial results. There were significant improvements in communication, cognition, and socialization. Additional positive effects were also reported, such as decline in inattention, restlessness, hyperactivity, and aggression. LDN can potentially help with self-injurious behavior as well.” “With that said, there was also a reduction in agitation, hyperactivity, temper tantrum, stereotyped behavior, and social withdrawal.”
LDN
Low dose naltrexone is available by prescription, also available as full dose 50 mg tablets 30 count. The price can be as low as $40 before insurance in $15 with insurance depending on copay.
The benefit of getting the 50 mg tablets and cutting them to 3-5mg each is a savings of over 90%. People often rinse/rub off the color coating in case it is FD&C that has lead & mercury. Then they crush the 50mg tablets with a mortal & pestil or a spoon & bowl. They add a drop of honey or a little stevia, and or monk fruit to taste better. Then they use a 5ml medicine doser (a couple dollars at any pharmacy) to add 5ml of water, mix together, draw back the 5ml of water now with the 50mg of naltrexone mixed in, & give 0.5ml per day which is roughly 5mg.
To eliminate any discomfort when taking it at bedtime, LDN is often started in the morning for a week or a couple days (sometimes at full dose) , then moved to the 5mg dose in the afternoon for a few days, then evening, then finally right at bedtime where it often works best. If it affects sleep, taking it any other time more comfortable will still work.
caution if:
on immunosuppressants
on high steroids (is often a substitute for steroids)
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